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American Society of Microbiology ABMM Sample Questions (Q109-Q114):
NEW QUESTION # 109
Metagenomic analysis of a bronchoalveolar lavage (BAL) sample from a patient with severe pneumonia reveals a complex microbial community with a high abundance of both bacterial and fungal sequences. This approach is particularly useful in identifying:
- A. The presence of fastidious or unculturable pathogens that may be missed by traditional methods.
- B. The presence of specific virulence factors expressed by the identified pathogens.
- C. The specific antibiotic susceptibility profile of the predominant bacterial pathogen.
- D. The relative proportions of different immune cell populations in the BAL fluid.
Answer: A
NEW QUESTION # 110
A clinical trial is evaluating the efficacy of a new antifungal agent against invasive aspergillosis. Serum galactomannan levels are being used as a biomarker to monitor the infection. A decrease in galactomannan levels during treatment would indicate:
- A. Concurrent infection with a non-Aspergillus mold.
- B. A false-positive result in the galactomannan assay.
- C. Successful clearance or reduction of the Aspergillus burden.
- D. Development of resistance to the antifungal agent.
Answer: C
NEW QUESTION # 111
A clinical microbiology laboratory is using flow cytometry to analyze lymphocyte subsets in a patient with suspected immunodeficiency. Which of the following cell surface markers is typically used to identify helper T cells?
- A. CD19
- B. CD56
- C. CD4
- D. CD8
Answer: C
NEW QUESTION # 112
A clinical microbiology laboratory is implementing a new real-time PCR assay for the direct detection of Chlamydia trachomatis in urine samples. To ensure the accuracy of negative results, it is essential to include:
- A. A high concentration of the Chlamydia trachomatis target sequence.
- B. A positive control containing Neisseria gonorrhoeae DNA.
- C. A melting curve analysis to confirm the specificity of the amplicon.
- D. An internal amplification control to detect PCR inhibition.
Answer: D
NEW QUESTION # 113
A previously healthy 28-year-old female develops a severe, watery diarrhea after attending a picnic where she consumed potato salad that had been left unrefrigerated for several hours. Stool culture reveals numerous Gram-positive bacilli. Further biochemical testing shows the organism is beta-hemolytic on blood agar and produces a heat-stable enterotoxin. The MOST likely causative agent is:
- A. Clostridium difficile
- B. Bacillus cereus
- C. Staphylococcus aureus
- D. Vibrio cholerae
Answer: B
NEW QUESTION # 114
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